The correlation between the change of Hounsfield units value and Modic changes in the lumbar vertebral endplate

Abstract Objectives To evaluate the changes of Hounsfield units (HU) value in different types Modic (MCs) and to analyze correlation between change HU area ratio MCs region, bone mineral density (BMD), degree intervertebral disc degeneration. Methods One hundred fifty-eight endplates with were included analyzed. values regions adjacent vertebral corresponding without measured. The region was defined as divided by endplate or sagittal plane. BMD measured Dual-energy x-ray absorptiometry (DXA). Degree degeneration evaluated based on Pfirrmann classification. According variables, descriptive statistics, Kolmogorove-Smirnov test, paired t-test, Wilcoxon signed-rank Independent-Samples T Test, Pearson analysis used. Results any are significantly higher than that ( P < 0.001). type III is I II MCs. positively correlated BMD. In levels Grade V degeneration, significant increased. Conclusions marrow increased most all had a positive Higher associated more severe